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Alex Schier: Global views of development

Harvard University Cambridge, USA & Biozentrum, University of Basel, Switzerland
When Dec 12, 2018
from 12:15 PM to 01:15 PM
Where Institute of Biology I, Hauptstraße 1, 79104 Freiburg, Lecture Hall, 1st Floor
Contact Name
Contact Phone 0761 203 67685
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Freiburg Neuroscience Lecture | Alex Schier

The development of systems ranging from brains to metastases is governed by regulatory factors that control specification trajectories and by cell division patterns that determine lineage relationships. I will illustrate how single-cell RNA sequencing and CRISPR-Cas9 genome editing provide new tools to reconstruct developmental trajectories and lineage trees at very large scales. I will discuss the opportunities and challenges for these technologies to provide new views of brain development (also see McKenna et al. Science 2016; Farrell et al. Science 2018; Pandey et al. Current Biology 2018; Raj et al. Nature Biotechnology 2018).

More about Alex Schier and his research:
Biozentrum, University of Basel, Switzerland